Avamist 27.5mcg Nasal Spray

Uses of Avamist 27.5mcg Nasal Spray

• Treatment of Sneezing and runny nose due to allergies

How does Avamist 27.5mcg Nasal Spray work?

Fluticasone Furoate is a corticosteroid, which works by decreasing the inflammation caused by allergies. It reduces inflammation by blocking the release of certain natural substances that cause allergic symptoms such as swelling, redness, and pain.

Side Effects of Avamist 27.5mcg Nasal Spray

Common side effects of Avamist include nosebleeds, headache, and nasal inflammation. This medication may lower the body's ability to fight infections, so caution should be exercised around individuals with contagious diseases like chickenpox, measles, or tuberculosis. 

Quick Suggestions:

• Avamist is a steroid medication used to alleviate symptoms associated with allergic rhinitis, such as a runny nose, sneezing, and sinus discomfort.
• It functions by obstructing the production of certain chemical messengers responsible for inflammation and allergies, thereby relieving nasal discomfort and irritation.
• It's crucial to adhere to your doctor's instructions for optimal benefits, and regular usage is recommended to achieve the full effect.
• Patients should also avoid situations that exacerbate symptoms, such as exposure to pollen and dust mites, and refrain from smoking.
• While it may take a few days for the spray to take full effect, if there's no improvement after a week, consulting your doctor is advisable.

Indication of Avamist 27.5mcg Nasal Spray

Fluticasone Furoate is used in the treatment of sneezing and runny nose due to allergies.

Pharmacology

Fluticasone Furoate is a synthetic trifluorinated corticosteroid with potent anti inflammatory activity. Like other corticosteroids Fluticasone Furoate is found to have a wide range of actions on multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, lymphocytes) and mediators (e.g.- histamine, eicosanoids, leukotrienes, cytokines) involved in inflammation.

Dosage & Administration of Avamist 27.5mcg Nasal Spray

Avamist is administered as a nasal spray, and the dosage and duration should be as per your doctor's recommendation. The correct method of application involves inserting the bottle tip into one nostril, closing the other nostril, and directing the spray towards the sides of the nostril while breathing gently. This process should be repeated for the other nostril.

Interaction

Avamist may lead to increased plasma concentrations of fluticasone when used with CYP4503A4 inhibitors like ritonavir. Therefore, it's essential to discuss all potential interactions with your doctor before starting any medication regimen.

Contraindications

Fluticasone Furoate nasal spray is contraindicated in patients with a hypersensitivity to any of its ingredients.

Pregnancy & Lactation

During pregnancy, Fluticasone Furoate nasal spray falls under Pregnancy Category C, indicating that there are no well-controlled studies in pregnant women to establish its safety. Therefore, its use during pregnancy should only be considered if the potential benefits to the mother outweigh the potential risks to the fetus. Pregnant women should consult with their healthcare provider before using Fluticasone Furoate nasal spray.

Regarding lactation, it is uncertain whether Fluticasone Furoate is excreted in human breast milk. However, other corticosteroids have been detected in breast milk. Therefore, caution should be exercised when administering Fluticasone Furoate to nursing women. Nursing mothers should discuss the risks and benefits of using Fluticasone Furoate nasal spray with their healthcare provider before starting the medication.

Precautions & Warnings

Precautions should be taken when using Avamist, especially in patients with recent nasal ulcers, surgery, or trauma. It is contraindicated in individuals with hypersensitivity to any of its ingredients. While systemic effects are minimal with recommended doses, larger doses should be avoided to minimize potential risks. Caution is advised during lactation, as data on distribution in breast milk are unknown.

Storage:

Store at a temperature not exceeding 30°C. Do not refrigerate. Protect from light and moisture. Keep out of the reach of children.